Sports consumption behaviour among generation Y in mainland China

The Chinese Government has relaxed its tight control over sport (Stensholt 2004), the country is set to host the 2008 Olympic Games and every major sport franchise in the world is making plans for a full assault on the Chinese market. The game is on in mainland China, however despite the excitement about the market there is little understanding of sport consumption in China or the attitudes and behaviours of potential sport consumers. The bulk of the literature in consumer behaviour within sports relates specifically to developed industrialised nations, specifically USA, Canada, Europe and Australia. Of particular interest to academics and practitioners alike should be the potential of the huge generation Y market in China. Generation Y (those born after 1978) represent not only a current lucrative market but also represent the future development of sport and sport consumption in China. This exploratory study has revealed that generation Y consumers in China exhibit sports consumption behaviours which differ in numerous respects from their counterparts in the USA and deserve deeper study

Understanding consumer responses to special event entertainment (SEE) in shopping centres

This paper reviews the literature on the use of entertainment in shopping centres and outlines the constructs believed to impact upon consumer’s responses to special event entertainment. Special event entertainment (SEE) refers to entertainment events or activities that are offered on an occasional, temporary or discontinued basis in shopping centres. Examples of SEE include school holiday entertainment and fashion shows (Parsons, 2003; Sit, Merrilees, & Birch, 2003). Using SEE, shopping centre management seeks to entice consumer patronage, increase patron traffic or promote the shopping centre brand. Despite the popularity of SEE in shopping centres, very little academic research (e.g. Parsons, 2003; Sit, Merrilees, & Birch, 2003) has either conceptually or empirically examined how consumers perceive or respond to SEE. This research presents a conceptual model that examines the determinants and outcomes of consumer responses to SEE, In particular, consumer responses to SEE are represented by SEE proneness and overall appreciation of SEE. These SEE responses are proposed to be determined by sensation-seeking tendencies and perceived value of SEE. Eight propositions are presented to explain the relationships of SEE responses with their determinants and outcomes. These relationships will be empirically tested in future research. Research implications of the conceptual model are also presented

The South Ellerbe Creek Greenway area neighborhood, Durham, North Carolina : an action-oriented community diganosis : findings and next steps of action

The following document describes the methods and results from an Action-Oriented Community Diagnosis (AOCD) conducted in the Greenway area of Durham, NC in the spring of 2004. This informal neighborhood is a residential area of downtown Durham and is bounded by three active neighborhood associations: Old North Durham, Trinity Park, and Duke Park. Interest in increasing Greenway residents’ participation in civic life, as well as concerns about crime and housing in the area, prompted Old North Durham’s president, Richard Mullinax, to initiate the AOCD process through the UNC School of Public Health. It was his hope that by investigating the area, a better understanding of community goals and future directions might be established. With the guidance of Mr. Mullinax, five students from the Department of Health Behavior and Health Education collected primary and secondary data concerning the Greenway area as well as Durham as a whole. Students strove to gain an understanding of (1) what it was like to live and work in this area of Durham, (2) who key leaders were, and (3) how the area was viewed by others. Towards this end, the team interviewed community residents, surrounding neighborhood association members, and service providers in order to identify strengths, concerns, and goals. An analysis of the team’s data revealed five primary domains: sense of community, crime and safety, housing, the Greenway trail, and youth. With the help of an advisory committee composed of Greenway area residents and members of the surrounding neighborhood associations, the team identified specific themes which were then presented to the larger community and service providers for discussion. These themes were: (1) Greenway residents want to know their neighbors better; (2) renters, landlords, and neighbors need to know their rights and responsibilities; (3) residents need to increase awareness of and participation in citizen safety initiatives like Partners Against Crime (PAC) II; (4) residents want to increase safety for children in the neighborhood; and (5) people want to feel safer using the Greenway Trail. At a well attended community forum, community members and service providers discussed these themes in small groups facilitated by the student team, and devised action steps for them to carry out. Above all, forum participants expressed a desire to continue discussion through subsequent meetings. Importantly, the student team identified several strengths that will serve the Greenway neighborhood well in its future endeavors. First, the team recognized several community leaders in the neighborhood, who, on an informal, block-by-block basis help to organize and protect residents. Second, residents and neighbors enjoy the central location and walkability of the Greenway area, and feel interest in this area will increase as revitalization of downtown Durham continues. Third, residents and neighbors appreciate the diversity of the Greenway area neighborhood, both in terms of ethnicity and in terms of housing. Finally, residents and neighbors enjoy the natural space provided by the Greenway Trail and Ellerbe Creek. These sources of pride within the community provide the basis for change. Action steps from the forum recommend that service providers and neighborhood association members continue to encourage and support the informal community networks established in the Greenway area neighborhood. Please see page 41 for a complete list of recommendations. Although residents did not express an interest in creating a formal neighborhood association, they were vocal in their desire to increase communication among themselves as well as collaboration with surrounding neighborhood associations and with service providers like the police and housing departments. The student team hopes that this report will provide supporting evidence and direction for encouraging cooperation among residents, neighborhood association members, and service providers.Master of Public Healt

A Pair of Dopamine Neurons Target the D1-Like Dopamine Receptor DopR in the Central Complex to Promote Ethanol-Stimulated Locomotion in Drosophila

Dopamine is a mediator of the stimulant properties of drugs of abuse, including ethanol, in mammals and in the fruit fly Drosophila. The neural substrates for the stimulant actions of ethanol in flies are not known. We show that a subset of dopamine neurons and their targets, through the action of the D1-like dopamine receptor DopR, promote locomotor activation in response to acute ethanol exposure. A bilateral pair of dopaminergic neurons in the fly brain mediates the enhanced locomotor activity induced by ethanol exposure, and promotes locomotion when directly activated. These neurons project to the central complex ellipsoid body, a structure implicated in regulating motor behaviors. Ellipsoid body neurons are required for ethanol-induced locomotor activity and they express DopR. Elimination of DopR blunts the locomotor activating effects of ethanol, and this behavior can be restored by selective expression of DopR in the ellipsoid body. These data tie the activity of defined dopamine neurons to D1-like DopR-expressing neurons to form a neural circuit that governs acute responding to ethanol

Acoustic sequences in non-human animals: a tutorial review and prospectus.

Animal acoustic communication often takes the form of complex sequences, made up of multiple distinct acoustic units. Apart from the well-known example of birdsong, other animals such as insects, amphibians, and mammals (including bats, rodents, primates, and cetaceans) also generate complex acoustic sequences. Occasionally, such as with birdsong, the adaptive role of these sequences seems clear (e.g. mate attraction and territorial defence). More often however, researchers have only begun to characterise - let alone understand - the significance and meaning of acoustic sequences. Hypotheses abound, but there is little agreement as to how sequences should be defined and analysed. Our review aims to outline suitable methods for testing these hypotheses, and to describe the major limitations to our current and near-future knowledge on questions of acoustic sequences. This review and prospectus is the result of a collaborative effort between 43 scientists from the fields of animal behaviour, ecology and evolution, signal processing, machine learning, quantitative linguistics, and information theory, who gathered for a 2013 workshop entitled, 'Analysing vocal sequences in animals'. Our goal is to present not just a review of the state of the art, but to propose a methodological framework that summarises what we suggest are the best practices for research in this field, across taxa and across disciplines. We also provide a tutorial-style introduction to some of the most promising algorithmic approaches for analysing sequences. We divide our review into three sections: identifying the distinct units of an acoustic sequence, describing the different ways that information can be contained within a sequence, and analysing the structure of that sequence. Each of these sections is further subdivided to address the key questions and approaches in that area. We propose a uniform, systematic, and comprehensive approach to studying sequences, with the goal of clarifying research terms used in different fields, and facilitating collaboration and comparative studies. Allowing greater interdisciplinary collaboration will facilitate the investigation of many important questions in the evolution of communication and sociality.This review was developed at an investigative workshop, “Analyzing Animal Vocal Communication Sequences” that took place on October 21–23 2013 in Knoxville, Tennessee, sponsored by the National Institute for Mathematical and Biological Synthesis (NIMBioS). NIMBioS is an Institute sponsored by the National Science Foundation, the U.S. Department of Homeland Security, and the U.S. Department of Agriculture through NSF Awards #EF-0832858 and #DBI-1300426, with additional support from The University of Tennessee, Knoxville. In addition to the authors, Vincent Janik participated in the workshop. D.T.B.’s research is currently supported by NSF DEB-1119660. M.A.B.’s research is currently supported by NSF IOS-0842759 and NIH R01DC009582. M.A.R.’s research is supported by ONR N0001411IP20086 and NOPP (ONR/BOEM) N00014-11-1-0697. S.L.DeR.’s research is supported by the U.S. Office of Naval Research. R.F.-i-C.’s research was supported by the grant BASMATI (TIN2011-27479-C04-03) from the Spanish Ministry of Science and Innovation. E.C.G.’s research is currently supported by a National Research Council postdoctoral fellowship. E.E.V.’s research is supported by CONACYT, Mexico, award number I010/214/2012.This is the accepted manuscript. The final version is available at http://dx.doi.org/10.1111/brv.1216

LSST: from Science Drivers to Reference Design and Anticipated Data Products

(Abridged) We describe here the most ambitious survey currently planned in the optical, the Large Synoptic Survey Telescope (LSST). A vast array of science will be enabled by a single wide-deep-fast sky survey, and LSST will have unique survey capability in the faint time domain. The LSST design is driven by four main science themes: probing dark energy and dark matter, taking an inventory of the Solar System, exploring the transient optical sky, and mapping the Milky Way. LSST will be a wide-field ground-based system sited at Cerro Pach\'{o}n in northern Chile. The telescope will have an 8.4 m (6.5 m effective) primary mirror, a 9.6 deg$^2$ field of view, and a 3.2 Gigapixel camera. The standard observing sequence will consist of pairs of 15-second exposures in a given field, with two such visits in each pointing in a given night. With these repeats, the LSST system is capable of imaging about 10,000 square degrees of sky in a single filter in three nights. The typical 5$\sigma$ point-source depth in a single visit in $r$ will be $\sim 24.5$ (AB). The project is in the construction phase and will begin regular survey operations by 2022. The survey area will be contained within 30,000 deg$^2$ with $\delta<+34.5^\circ$, and will be imaged multiple times in six bands, $ugrizy$, covering the wavelength range 320--1050 nm. About 90\% of the observing time will be devoted to a deep-wide-fast survey mode which will uniformly observe a 18,000 deg$^2$ region about 800 times (summed over all six bands) during the anticipated 10 years of operations, and yield a coadded map to $r\sim27.5$. The remaining 10\% of the observing time will be allocated to projects such as a Very Deep and Fast time domain survey. The goal is to make LSST data products, including a relational database of about 32 trillion observations of 40 billion objects, available to the public and scientists around the world.Comment: 57 pages, 32 color figures, version with high-resolution figures available from https://www.lsst.org/overvie

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN